Which of the following is a commonly used antibiotic for treating skin infections?

Prepare efficiently for the USMLE Step 2 with our Antibiotics and Treatments Exam. Explore detailed questions, gain insights with comprehensive explanations, and boost your confidence for success! Ace your exam!

Clindamycin is a commonly used antibiotic for treating skin infections, particularly those caused by anaerobic bacteria and certain strains of Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA). It is often preferred for its effectiveness against these bacteria in conditions like cellulitis, abscesses, and certain types of skin and soft tissue infections.

Clindamycin's mechanism of action involves inhibiting bacterial protein synthesis, which makes it effective against a variety of Gram-positive organisms and some anaerobes. Its oral formulation is particularly beneficial for outpatient treatment, and it can also be used intravenously in more severe cases.

In contrast, while other antibiotics listed may be used for different types of infections, they do not have the same level of specific utility for skin infections as clindamycin. For example, Ceftriaxone is primarily used for systemic infections and not typically first-line for skin infections, Amikacin is an aminoglycoside usually reserved for severe Gram-negative infections, and Metronidazole is mainly effective against anaerobic infections and protozoan infections, not specifically targeting common pathogens in skin infections.

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