Which antibiotic is effective against Pseudomonas aeruginosa?

Piperacillin-tazobactam is a broad-spectrum antibiotic commonly used in clinical practice, particularly for infections caused by Pseudomonas aeruginosa. This combination includes the beta-lactam antibiotic piperacillin, which has inherent activity against Pseudomonas, paired with tazobactam, a beta-lactamase inhibitor that helps protect piperacillin from being degraded by certain bacterial enzymes.

In the context of treating Pseudomonas infections, piperacillin-tazobactam is often utilized in serious infections due to its effectiveness, particularly in hospital settings where this pathogen is prevalent. Its activity covers a wide range of beta-lactamase enzymes, making it effective against resistant strains, which is important in managing infections that may be complicated by resistance mechanisms.

Other antibiotics mentioned may have some activity against Pseudomonas, but piperacillin-tazobactam is considered one of the first-line treatments due to its strong efficacy and safety profile. For instance, ciprofloxacin is also effective against Pseudomonas, but its clinical use may be more limited compared to piperacillin-tazobactam for serious infections, particularly those requiring broad-spectrum coverage. An