Which antibiotic is contraindicated in pregnancy due to potential fetal harm?

Prepare efficiently for the USMLE Step 2 with our Antibiotics and Treatments Exam. Explore detailed questions, gain insights with comprehensive explanations, and boost your confidence for success! Ace your exam!

Tetracyclines are contraindicated in pregnancy primarily due to their potential to cause fetal harm, particularly in relation to the developing skeleton and teeth. This class of antibiotics can lead to discoloration of teeth and may inhibit bone growth in the fetus, as they can bind to calcium in the bones and teeth.

Other antibiotics listed have varying levels of safety in pregnancy. Amoxicillin is generally considered safe and is often used for bacterial infections in pregnant women. Metronidazole, while used with caution, has also been deemed acceptable for use in certain infections during pregnancy, although there are concerns about its use in the first trimester. Clindamycin is generally safe as well and is used to treat various infections in pregnancy without the same risk of causing harm to the developing fetus as tetracyclines do.

The specific risks associated with tetracycline use in pregnancy make it essential to avoid this group in order to protect the health and development of the fetus.

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